To Study the Effect of Adjunctive Oral Methylprednisolone Therapy in Pediatric Urinary Tract Infection
Status:
Unknown status
Trial end date:
2015-12-01
Target enrollment:
Participant gender:
Summary
Purposes of this study will be as follows:
1. To design a prospective, randomized, and open-labeled study to investigate the effect
and the side effect of MPD in combination with conventional antibiotics to affect
clinical course, outcome, and medical expenses.
2. To compare level of the urinary and serum cytokines before and after received MPD for
the following sub-aim:
I. To determine the population who is benefit from MPD to reduce the severity of clinical
course and subsequent renal scarring.
II. To understand the mechanism by which the MPD could shorten the clinical course and reduce
the renal scarring.