Overview

To Reduce the Use of Chemotherapy in Postmenopausal Patients With ER-positive and HER2-positive Breast Cancer (TOUCH)

Status:
Recruiting
Trial end date:
2022-08-01
Target enrollment:
Participant gender:
Summary
This is a phase II open-label, multicentre, randomized trial. The study assesses the treatment of postmenopausal patients with hormone receptor positive/HER2 positive early breast cancer with neoadjuvant palbociclib in combination with hormonal therapy and HER2 blockade, versus the treatment with paclitaxel in combination with HER2 blockade.
Phase:
Phase 2
Details
Lead Sponsor:
International Breast Cancer Study Group
Collaborators:
Hoffmann-La Roche
Pfizer
Treatments:
Albumin-Bound Paclitaxel
Letrozole
Paclitaxel
Palbociclib
Pertuzumab
Trastuzumab