To Determine Whether Galactomannan Test Will Help to Detect Fungal Infections Early and Hence Start Treatment Early
Status:
Completed
Trial end date:
2009-06-30
Target enrollment:
Participant gender:
Summary
Chemotherapy lowers the white blood cell count or weakens the immune system for a long time.
This puts the patients at a high risk of getting a serious fungal infection of the internal
organs or blood. One of these infections is caused by a mold called Aspergillus and can be
life threatening. Usually doctors give preventive antifungal therapy to try to lower the risk
of this infection. Despite this, patients are still at risk of getting fungal infection. This
study is thus designed to test Galactomannan - a component of cell wall of Aspergillus and
hence detect and treat fungal infection early.
Phase:
Phase 3
Details
Lead Sponsor:
Singapore General Hospital
Collaborator:
National University Hospital, Singapore
Treatments:
Amphotericin B Amphotericin B, deoxycholate drug combination Deoxycholic Acid Liposomal amphotericin B