Overview To Determine The Efficacy and Safety of GDC-0449 in Patients With Basal Cell Nevus Syndrome (BCNS) Status: Completed Trial end date: 2014-01-01 Target enrollment: Participant gender: Summary The purpose of this study is to reduce the number of new surgically eligible BCCs by 50% appearing during month 3-18 of medication ingestion. Phase: Phase 2 Details Lead Sponsor: Children's Hospital & Research Center OaklandUCSF Benioff Children's Hospital OaklandCollaborator: Genentech, Inc.