To Define the Role of GLP-1 for Improving Glucose Homeostasis in Humans Following Gastric Bypass Surgery
Status:
Completed
Trial end date:
2015-11-17
Target enrollment:
Participant gender:
Summary
There is a marked and long-lasting improvement in glucose homeostasis that follows Roux-en-y
gastric bypass surgery (RYGB) in humans. This improvement has been attributed in large part
to an intestinal hormone, called GLP-1, that is released into the circulation immediately
after eating. The purpose of this study is to determine if GLP-1 mediates the beneficial
effects of RYGB surgery on glucose homeostasis in humans.
Phase:
Phase 1
Details
Lead Sponsor:
Washington University School of Medicine
Collaborator:
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)