To Compare Efficacy of Low Dose Diclofenac (25mg) in Management of Postoperative Pain After Periodontal Flap Surgery
Status:
Completed
Trial end date:
2017-05-21
Target enrollment:
Participant gender:
Summary
Pain after periodontal surgical procedures is a common manifestation. The perception of pain
is highly subjective and varies substantially among individuals. Many factors affect pain
perception, such as the nature, duration, and extent of the surgery and psychological aspects
(e.g., stress and anxiety). Pain after periodontal surgery is an example of acute dental pain
of mild to moderate severity. Non-steroidal anti-inflammatory drugs (NSAIDs) have a
significant advantage in the control of pain after periodontal or oral surgical procedures.
Diclofenac is a powerful anti-inflammatory and analgesic drug that is well suited for local
use in the oral cavity. Diclofenac competes with arachidonic acid in a dose dependent manner
for binding with platelet COX. This results in decreased production of PG and thus reduces
inflammation, swelling and pain.
As Diclofenac associated with many adverse effects, like gastric irritability, nausea,
headache, dizziness. Undesirable effects may be minimized by using the lowest effective dose
for the shortest duration necessary to control symptoms. As many of clinical trials have
suggested Diclofeanc 50 mg alleviates the postoperative pain. So main aim of the study was to
evaluate the effectiveness of low dose Diclofenac(25mg) in reducing the post operative pain
after periodontal flap surgeries. Thus comparing the effects of low dose Diclofenac and
Diclofenac 50mg for reducing post-operative pain.