Tizanidine and Superficial Cervical Block on Pain After Thyroidectomy
Status:
Completed
Trial end date:
2016-12-01
Target enrollment:
Participant gender:
Summary
Thyroid surgery is a quite painful procedure performed in a sensitive skin area of the human
body. Unless pain is treated adequately thyroid surgery may cause severe postoperative pain
and discomfort for the patients.
a2-Agonists are sympatholytic and centrally acting antihypertensive agents. In addition to
their hypotensive effect, a2-agonists are also used in anesthetic practice for their sedative
and analgesic effects. Tizanidine is a centrally acting a2-agonist with muscle relaxant,
sedative and anxiolytic properties. This drug is widely used for the treatment of spasticity
and has recently been used to treat musculoskeletal pain conditions.
Ultrasound (US) guidance during regional anesthesia practices has been a revolutionary
advancement to improve success and safety of regional anesthesia. Analgesic effect of US
guidance superficial cervical plexus block (SCPB) in patients undergoing thyroid surgery has
not been reported yet.
The aim of this study was to evaluate the analgesic effect of preemptive oral single dose
tizanidine and US guidance SCPB in patients undergoing elective thyroid surgery. The
investigators hypothesis that: Tizanidine and US guided SCPB can reduce the pain scores,
analgesic consumption, analgesic related side effects.