Titrated Oral Compared With Vaginal Misoprostol for Labor Induction at Term

• Status: Completed
• Trial end date: 2007-03-01
• Target enrollment: 0
• Participant gender: Female

Summary

The purpose of this study was to estimate the safety and efficacy of titrated oral misoprostol compared with vaginal route for labor induction at term.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: China Medical University Hospital
• Treatments: Misoprostol

Criteria

Inclusion Criteria:

• 34 to 42 weeks of gestation

• live singleton

• Bishop score < or = 6

• reassuring fetal heart beat pattern

Exclusion Criteria:

• nonreassuring fetal heart beat pattern

• parity ovr five

• any contraindication to labor and/or vaginal delivery

• uterine scar

• suspected placental abruption with abnormal FHR pattern

• vaginal bleeding other than "bloody show"

• cervical dilatation of > or = 4 cm

• uterine contractions > or = 3 in 10 minutes

• significant maternal cardiac, renal or hepatic disease

• hypersensitivity to misoprostol or prostaglandin analogs