Tirapazamine Combined With Chemo and RT in Limited-Stage Small Cell Lung Cancer
Status:
Completed
Trial end date:
2009-08-01
Target enrollment:
Participant gender:
Summary
This phase II trial is studying how well giving tirapazamine together with cisplatin,
etoposide, and radiation therapy works in treating patients with limited-stage small cell
lung cancer. Drugs used in chemotherapy, such as cisplatin and etoposide, work in different
ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses
high-energy x-rays to damage tumor cells. Tirapazamine may make the tumor cells more
sensitive to chemotherapy and radiation therapy. Combining chemotherapy and radiation therapy
with tirapazamine may kill more tumor cells.