Overview

Tipifarnib and Sorafenib Tosylate in Treating Patients With Biopsiable Advanced Cancer

Status:
Completed
Trial end date:
2017-03-01
Target enrollment:
Participant gender:
Summary
This phase I trial studies the side effects and best dose of tipifarnib when given together with sorafenib tosylate in treating patients with biopsiable cancer that has spread to other places in the body and usually cannot be cured or controlled with treatment. Tipifarnib and sorafenib tosylate may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the cancer.
Phase:
Phase 1
Details
Lead Sponsor:
National Cancer Institute (NCI)
Treatments:
Niacinamide
Sorafenib
Tipifarnib