Overview

Tiotropium Induced Bronchodilation in Lung CT Scored Emphysema

Status:
Completed
Trial end date:
2005-08-01
Target enrollment:
0
Participant gender:
All
Summary
To evaluate if tiotropium (Spiriva)induced bronchodilation of inspiratory capacity in patients with moderate to severe copd subjected to metronome paced hyperventilation induced dynamic hyperinflation is dependent upon the extent of underlying emphysema as determined by high resolution-thin section CT lung.
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Gelb, Arthur F., M.D.
Collaborators:
Boehringer Ingelheim
Pfizer
Treatments:
Tiotropium Bromide
Criteria
Inclusion Criteria

- moderate to severe copd

Exclusion Criteria

- unable to tolerate tiotropium

- unable to perform metronome paced hyperventilation induced dynamic hyperinflation