Overview

Tinidazole Versus Cefazolin Antibiotic Prophylaxis of Vaginal and Abdominal Hysterectomy

Status:
Unknown status

Trial end date:
2008-12-01

Target enrollment:
0

Participant gender:
Female

Summary

Purpose: to compare the efficacy of tinidazole and cefazolin on the prophylaxis of the febrile and infectious morbidity after vaginal or abdominal hysterectomy. Methods: A randomized clinical trial carried out at the Women's Integrated Healthcare Center (CAISM)/UNICAMP, Campinas, Brazil. Women undergoing to total vaginal or abdominal hysterectomy were randomly enrolled into one of these three groups of antibiotic prophylaxis: tinidazole, cefazolin or an association of both.

Phase:

N/A

Accepts Healthy Volunteers?

Details

Lead Sponsor:

University of Campinas, Brazil

Treatments:

Anti-Bacterial Agents
Antibiotics, Antitubercular
Cefazolin
Imidazole
Tinidazole

Criteria

Inclusion Criteria:

- women undergoing to hysterectomy due to non-oncologic causes

Exclusion Criteria:

- previous pelvic infection

- antibiotic use within 7 days before surgery

- study drugs allergy

- immuno-incompetence

- urinary tract infection