Time-dependent Amiodarone Treatment in Atrial Fibrillation
Status:
Completed
Trial end date:
2009-11-30
Target enrollment:
Participant gender:
Summary
Sixty consecutive emergency patients with newly diagnosed Atrial Fibrillation were randomized
into two groups. The first received intravenous amiodarone infusions continuously for 24
hours; the second received Amiodarone until sinus rhythms was reached or for up to 72 hours.
The efficacy and safety of administering intravenous infusions of amiodarone for up to 72
hours were investigated and compared to the efficacy and safety of administering a standard
24 hours infusion of amiodarone. Specifically, the use of up to 72 hours infusions was
considered as a new strategy to improve rates of conversion to sinus rhythm without altering
the safety profile of the drug.
Phase:
Phase 4
Details
Lead Sponsor:
Instituto de Cardiología y Medicina Vascular Hospital Zambrano-Hellion Tec Salud