Tight Versus Liberal Blood Glucose Control in Adult Critically Ill Patients
Status:
Recruiting
Trial end date:
2026-01-01
Target enrollment:
Participant gender:
Summary
Critically ill patients usually develop hyperglycemia, which is associated with an increased
risk of morbidity and mortality. Controversy exists on whether targeting normal blood glucose
concentrations with insulin therapy, referred to as tight blood glucose control (TGC)
improves outcome of these patients, as compared to tolerating hyperglycemia. It remains
unknown whether TGC, when applied with optimal tools to avoid hypoglycemia, is beneficial in
a context of withholding early parenteral nutrition. The TGC-fast study hypothesizes that TGC
is beneficial in adult critically ill patients not receiving early parenteral nutrition, as
compared to tolerating hyperglycemia.
Phase:
Phase 3
Details
Lead Sponsor:
KU Leuven
Collaborators:
Research Foundation Flanders Universitaire Ziekenhuizen Leuven