Tight Glycemic Control in Acute Exacerbations of COPD
Status:
Unknown status
Trial end date:
2012-12-01
Target enrollment:
Participant gender:
Summary
Glucose control has been shown as an important and independent prognostic factor in several
acute conditions in hospitalized patients, including Acute MI, stroke, cardiac surgery and in
critical care units.
Patients with acute exacerbation of COPD (AECOPD)and diabetes treated with insulin had a
longer in-patient stay and more frequent isolation of Gram negative bacteria from sputum than
those without diabetes.Hyperglycemia (>11 mmol/l) on admission predicted failure of
non-invasive ventilation and infectious pulmonary complications in patients admitted to the
ICU with acute respiratory failure caused by severe AECOPD.
The primary goal of this study is to test the hypothesis that in AECOPD, tight glycemic
control during hospital stay will improve outcome of hospitalization.
The secondary goal of this study is to test new ways in controlling patients in the internal
medicine ward.