The aim of the study is to examine the effects of fine titration of thyroxine dosage on
symptoms of hypothyroidism, wellbeing and quality of life. The hypothesis is that symptoms of
hypothyroidism, wellbeing and quality of life will be improved in thyroxine-treated subjects
when serum thyrotropin (TSH) is suppressed and/or in the lower reference range, compared to
when TSH is in the upper reference range.