Overview

Thyroid Lobectomy With or Without Levothyroxine Treatment Postoperatively

Status:
Completed
Trial end date:
2008-12-01
Target enrollment:
0
Participant gender:
All
Summary
The aim of this study was to compare the prevalence of recurrent nodular goiter in the contralateral thyroid lobe among patients after unilateral thyroid lobectomy for unilateral multinodular goiter receiving versus not receiving prophylactic levothyroxine treatment postoperatively in a five-year follow-up of a randomized study
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Jagiellonian University
Criteria
Inclusion Criteria:

- unilateral multinodular goiter with normal appearing on ultrasound of the neck
contralateral thyroid lobe, in a patient in euthyroid state

Exclusion Criteria:

- bilateral multinodular goiter, enlargement of contralateral thyroid lobe (volume on
ultrasound >10 ml), suspicion of thyroid cancer, previous thyroid surgery,
thyroiditis, subclinical or clinically overt hypothyroidism or hyperthyroidism,
pregnancy or lactation, age < 18 years or > 65 years, ASA 4 grade (American Society of
Anesthesiology), and inability to comply with the follow-up protocol