Thymoglobulin Induction Therapy in Kidney Transplantation (6mg/kg vs 4mg/kg)
Status:
Unknown status
Trial end date:
2018-05-01
Target enrollment:
Participant gender:
Summary
This is a prospective randomized controlled study to evaluate feasibility and safety of early
steroid withdrawal after 6mg/kg vs 4.5mg/kg Thymoglobulin induction therapy in kidney
transplantation. Patients are enrolled from June, 2015 for 24 months. They are randomized to
either 6mg/kg or 4.5mg/kg Thymoglobulin induction group. Steroid withdrawal is done within
one week after kidney transplantation for all the patients. Maintenance immunosuppressants
are Tacrolimus and Mycophenolate mofetil (or Myfortic). Primary outcome is a composite of
biopsy-proven acute rejection, delayed graft function, graft loss or death within one year
post transplant.