Thrombolysis in Pediatric Stroke (TIPS) is a five-year multi-center international safety and
dose-finding study of intravenous (IV) tPA in children with acute ischemic stroke (AIS) to
determine the maximal safe dose of intravenous Tissue Plasminogen Activator (IV-tPA) among
three doses (0.75. 0.9, 1.0 mg/kg) for children age 2-17 years within 4.5 hours from onset of
acute AIS.
Phase:
Phase 1
Details
Lead Sponsor:
Seattle Children's Hospital
Collaborators:
Alberta Children's Hospital McMaster University Medical College of Wisconsin The Hospital for Sick Children University of Texas at Austin