Three-times-weekly Versus Daily Growth Hormone (GH) Treatment in naïve GH-deficient Children
Status:
Completed
Trial end date:
2017-01-01
Target enrollment:
Participant gender:
Summary
Growth hormone (GH) treatment in patients with GH deficiency (GHD) is commonly administered
daily, although the pulsatile GH secretion is unlikely to be achieved and this regimen is
often not complied. The auxological effect of three injections per week (TIW) regimen is
controversial, while the metabolic effects were never evaluated in children. The objective of
this study was to evaluate whether two different regimens of weekly injections could lead to
similar auxological and metabolic effects in children with GHD.