Three Month Treatment of Growth Hormone Releasing Hormone (GHRH) in the Elderly
Status:
Terminated
Trial end date:
2011-08-01
Target enrollment:
Participant gender:
Summary
The purpose of the study is to evaluate the effect of a naturally occurring hormone, called
Growth Hormone Releasing Hormone (GHRH) on the muscle, bone, and fat tissues of the body.
GHRH stimulates the production of growth hormone (GH), which regulates the build up of many
tissues in the body, including muscles and bones. Many elderly people have low levels of GH.
The overall goal of this research is to determine the efficacy of GHRH to raise levels of GH
and improve these body tissues. Healthy men and women age 65 and older will receive GHRH in
four doses nightly for 12 weeks and assessed for changes in muscle strength, body mass,
physical performance, and how the body uses sugar.
Phase:
Phase 2
Details
Lead Sponsor:
University of Pennsylvania
Collaborator:
National Institute on Aging (NIA)
Treatments:
Growth Hormone-Releasing Hormone Hormones Hormones, Hormone Substitutes, and Hormone Antagonists