Overview

Three Chemo Regimens as an Adjunct to ART for Treatment of Advanced AIDS-KS

Status:
Completed
Trial end date:
2019-08-29
Target enrollment:
Participant gender:
Summary
This study was done to compare the safety and efficacy of three combination treatments for Kaposi's Sarcoma (KS) and AIDS: 1. Etoposide (ET) plus co-formulated Efavirenz/Emtricitabine/Tenofovir Disoproxil Fumarate (EFV/FTC/TDF) (ET+ART), 2. Bleomycin and Vincristine (BV) plus co-formulated EFV/FTC/TDF (BV+ART), 3. Paclitaxel (PTX) plus co-formulated EFV/FTC/TDF (PTX+ART).
Phase:
Phase 3
Details
Lead Sponsor:
AIDS Clinical Trials Group
Collaborators:
AIDS Malignancy Consortium
National Cancer Institute (NCI)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of Dental and Craniofacial Research (NIDCR)
Treatments:
Bleomycin
Efavirenz
Efavirenz, Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination
Emtricitabine
Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination
Etoposide
Paclitaxel
Tenofovir
Vincristine