Overview

Thorough ECG (Electrocardiogram) and Drug Interaction Study With Anetumab Ravtansine and Itraconazole

Status:
Completed
Trial end date:
2019-08-05
Target enrollment:
Participant gender:
Summary
Characterize the safety, tolerability, ECG effects, pharmacokinetics and immunogenicity of anetumab ravtansine given as single agent and after inhibition of CYP3A4 and P-gp by concomitant administration of itraconazole in subjects with mesothelin-expressing advanced solid cancers
Phase:
Phase 1
Details
Lead Sponsor:
Bayer
Treatments:
Hydroxyitraconazole
Immunoconjugates
Itraconazole
Maytansine