60 patients ASA I-III, undergoing open nephrectomy will be randomly assigned into one of two
groups, namely group A (n=30), where a thoracic paravertebral block will be performed
preoperatively and a paravertebral catheter for continuous and patient controlled bolus local
anesthetic (ropivacaine) doses will be inserted and group B (n=30) where morphine IV will be
administered at the beginning and the end of operation and postoperatively through patient
controlled IV doses. NRS scores in static and dynamic conditions, complications, patient
satisfaction, oxidative stress (through lactic acid, superoxide dismutase, malondialdehyde)
and NGAL pre- and postoperatively, will be recorded.
Phase:
Phase 2
Details
Lead Sponsor:
Asklepieion Voulas General Hospital
Collaborators:
Chryssoula Staikou Ioannis Karavokyros Michail Tsagkaris