Thoracic Paravertebral Block in Pain Management After Renal Surgery
Status:
Completed
Trial end date:
2014-12-01
Target enrollment:
Participant gender:
Summary
Objective: The objective of the study was to assess the usefulness of ThPVB in postoperative
pain management after open renal resection surgery.
Design, setting, participants: It was a prospective, randomised, open label study held in a
university hospital between 08.2013-12.2014. 58 Patients enrolled in the study were scheduled
for elective open renal surgery (open nephrectomy or open nephron-sparing surgery) and
randomised into two groups - group PVB (n=27) and group GEN (n=31).
Interventions: PVB group received preoperative ThPVB with 0,5% bupivacaine followed by
general anaesthesia. GEN group received standard general anaesthesia. Both groups were
treated postoperatively with oxycodone IV PCA (patient controlled analgesia) combined with
non-opioid analgesics as rescue drugs. The investigators recorded pain severity in VAS,
oxycodone requirement in time points, total oxycodone requirement, and sedation levels
throughout the first 48h. The investigators measured opioid related adverse events 24 and 48
h postoperatively and patients satisfaction 48h postoperatively.