Thiamine as an Adjunctive Therapy in Cardiac Surgery
Status:
Completed
Trial end date:
2015-08-01
Target enrollment:
Participant gender:
Summary
The main purpose of this pilot study is to test the effects of thiamine (vitamin B1)
administration before and after major cardiac surgery. Half of patients will receive thiamine
and the other half will receive placebo.
The investigators' main hypothesis is that thiamine will improve cellular oxygen consumption
and lead to decreased levels of post-operative lactate levels and ultimately improved patient
outcomes.
Phase:
Phase 2
Details
Lead Sponsor:
Beth Israel Deaconess Medical Center
Collaborators:
American Heart Association University of Aarhus
Treatments:
Pharmaceutical Solutions Thiamine Vitamin B Complex Vitamins