Thiamine Supplement in Patients With Severe Hyperthyroidism
Status:
Completed
Trial end date:
2016-07-01
Target enrollment:
Participant gender:
Summary
Thyrotoxicosis is a hypermetabolic state in which there is increased utilization of thiamine.
Thiamine deficiency has been observed in association with hyperthyroidism. Several studies
documented that thiamine treatment could improve signs and symptoms of congestive heart
failure, or even improve left ventricular ejection fraction in patients without
thyrotoxicosis. This pilot study aims to evaluate prevalence of thiamine deficiency and
assess improvement of cardiovascular function after receiving thiamine supplement in
thyrotoxic patients.