Overview
Therapy of Ventilator-associated Tracheobronchitis Caused by Gram Negative Bacteria With Nebulized Colistin
Status:
Unknown status
Unknown status
Trial end date:
2017-12-01
2017-12-01
Target enrollment:
0
0
Participant gender:
All
All
Summary
The purpose of this study is to determine whether inhaled colistin is effective in the treatment of ventilator associated tracheobronchitis due to gram negative organism susceptible to colistin.Phase:
Phase 3Accepts Healthy Volunteers?
NoDetails
Lead Sponsor:
Mahidol UniversityTreatments:
Colistin
Criteria
Inclusion Criteria:- Clinical diagnosis of ventilator-associated tracheobronchitis caused by gram negative
organism.
- Expected to survive more than 48 hours after enrollment.
- Received intravenous colistin not more than 48 hours prior enrollment.
Exclusion Criteria:
- Pregnancy and Lactation
- Allergy to colistin
- Serum creatinine > 4 mg/dl or GFR decreased more than 75% from baseline