Therapeutics in Active Prostate Cancer Surveillance
Status:
Completed
Trial end date:
2019-07-25
Target enrollment:
Participant gender:
Summary
Testing if short-term use of apalutamide can reduce image defined tumour volumes in men with
detectable lesion on multi-parametric Magnetic Resonance Imaging (mpMRI) and being managed by
Active Surveillance. The trial will also evaluate the tolerability and side effect profile of
men on AS using short term apalutamide and patient acceptability as a therapeutic strategy,
as well as determining feasibility of a larger prospective randomised trial of apalutamide.