Therapeutic Strategies for Microvascular Dysfunction in Type 1 Diabetes
Status:
Not yet recruiting
Trial end date:
2027-06-01
Target enrollment:
Participant gender:
Summary
We will test the hypothesis that, in adults with type 1 diabetes (T1D), glucagon-like
peptide-1 receptor agonism (GLP-1RA, i.e. dulaglutide) and exercise training each enhance
insulin-mediated skeletal muscle microvascular perfusion via attenuating endothelial
oxidative stress and thereby improving endothelial function.