Therapeutic Intensification Plus Immunomodulation to Decrease the HIV-1 Viral Reservoir
Status:
Completed
Trial end date:
2014-06-01
Target enrollment:
Participant gender:
Summary
The objective of this study is to discover a new approach in which human immunodeficiency
virus (HIV) can be eradicated from an infected individual by intensified antiretroviral
treatment coupled with immunomodulation. The hypothesis is that eradication is possible only
if very potent antiretroviral drugs are delivered in conjunction with an immunomodulatory
agent that simultaneously attack the viral reservoirs.
Phase:
Phase 2
Details
Lead Sponsor:
Robert L. Murphy
Collaborators:
Merck Sharp & Dohme Corp. National Institute of Allergy and Infectious Diseases (NIAID) Objectif Recherche Vaccins SIDA Pfizer