Therapeutic Efficacy in Women With Stress Urinary Incontinence

• Status: Not yet recruiting
• Trial end date: 2024-12-31
• Target enrollment: 0
• Participant gender: Female

Summary

We will get the impact of duloxetine versus imipramine on therapeutic efficacy in women with SUI.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Far Eastern Memorial Hospital
• Treatments: Duloxetine Hydrochloride; Imipramine

Criteria

Inclusion Criteria:

• Female patients over 25 years old with stress urinary incontinence.

• Patients who are currently not considered for surgical treatment.

• Patients who have undergone regular Kegel exercises but have poor results.

Exclusion Criteria:

• The result of urodynamic examination, if the main cause of urinary incontinence is detrusor overactivity.

• Those who are taking or plan to take monoamine oxidase inhibitor (MAOI) inhibitors.

• Patients with acute myocardial infarction.

• Those who are allergic to duloxetine, imipramine and dibenzazepine tricyclic antidepressants.

• Patients with uncontrolled narrow-angle glaucoma.

• Pregnant women.

• Those who are contraindicated to duloxetine or imipramine.

• Patients with suicidal ideation and behavior.