Therapeutic Effect of Sodium Selenite on Oxidative Stress in Patients With Severe Sepsis

• Status: Completed
• Trial end date: 2013-12-01
• Target enrollment: 0
• Participant gender: All

Summary

This study looked at parenteral administration of selenium to septic patients and subsequently monitored dynamic changes of selected activities of antioxidant enzymes and the development of clinical status.

• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Pavol Jozef Safarik University
• Treatments: Selenious Acid; Selenium; Sodium Selenite

Criteria

Inclusion Criteria:

• sepsis, severe sepsis or septic shock, APACHE II score between 19 and 24 points after admission

Exclusion Criteria:

• mechanical ventilation for less than 24h, neuromuscular disease and terminal illness were also excluding criteria