Therapeutic Effect of Cytoreductive Radical Prostatectomy in Men With Newly Diagnosed Metastatic Prostate Cancer
Status:
Recruiting
Trial end date:
2022-09-01
Target enrollment:
Participant gender:
Summary
This randomized phase II trial studies how well surgical removal of the prostate and
antiandrogen therapy with or without docetaxel work in treating men with newly diagnosed
prostate cancer that has spread to other places in the body. Androgens can cause the growth
of prostate cancer cells. Antiandrogen therapy may lessen the amount of androgens made by the
body. Drugs used in chemotherapy, such as docetaxel work in different ways to stop the growth
of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping
them from spreading. Surgery, antiandrogen therapy and docetaxel may work better in treating
participants with prostate cancer.