Therapeutic Effect of Cassia Seed in Obesity of Patients With Schizophrenia

• Status: Completed
• Trial end date: 2019-10-31
• Target enrollment: 0
• Participant gender: All

Summary

Schizophrenia patients with anti-psychotics have decreased psychiatric symptoms, but have increased the generation of overweight or obesity. There is correlation between obesity, diabetes mellitus, metabolic syndrome, hypertension, hyperlipidemia and cardiovascular disorders. Cassia seed is one of traditional Chinese herbs, that can decline blood lipedema effect. Therefore, the purpose of the present study was to design a randomized, double blind, control group study to assess the therapeutic effect of Cassia seed in schizophrenia patients with obesity.

• Phase: Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Calo Psychiatric Center

Criteria

Inclusion Criteria:

• age 18 to 65 years

• diagnosed as schizophrenia at least more 6 months

• no major systemic illnesses based on physical examinations and laboratory test results

• BMI >= 24, WC >= 80 cm in female, WC >= 90 cm in male

Exclusion Criteria:

• participants were pregnant and lactating women

• allergy to Cassia

• SGOT or SGPT more than 2 times normal level

• BUN or creatinine more than normal level

• Fasting blood glucose (serum) > 140 mg/dL, systolic blood pressure > 180 mmHg, diastolic blood pressure > 110 mmHg, serum triglyceride > 400 mg/dL