The Use of Nesiritide in Thoracic Aneurysm Repair to Prevent Acute Renal Failure

• Status: Unknown status
• Trial end date: 2007-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this trial is to study the use of nesiritide in thoracic aneurysm repair to prevent acute renal failure.

The study hypothesis: Nesiritide, given prophylactically prior to surgery may prevent acute renal failure requiring dialysis and/or decrease mortality.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Ejaz, Abulate A, MD
• Treatments: Natriuretic Peptide, Brain

Criteria

Inclusion Criteria:

• Age 18 years or older

• Undergoing thoracic aortic aneurysm surgery

• Impaired renal function

Exclusion Criteria:

• Prior history of allergy/adverse reaction to Nesiritide

• History of any organ transplant

• Preoperative intra-aortic balloon pump (IABP)

• Decompensated congestive heart failure (CHF)