The Use of Microneedles With Topical Botulinum Toxin for Treatment of Palmar Hyperhidrosis
Status:
Completed
Trial end date:
2016-08-02
Target enrollment:
Participant gender:
Summary
Hyperhidrosis or sweating of palms results from the overactivity of sweat glands and leads to
psychosocial impairment with reduction in quality of life in those that are affected.
Injection of botulinum toxin has been shown to be effective in reducing the symptoms of
hyperhidrosis with associated improvement in quality of life, but is usually very painful.
Microneedles are a different modality for transdermal drug penetration without the pain. This
study aims to understand if botulinum toxin A can be delivered topically after microneedle
pretreatment in hopes of developing a minimally painful treatment protocol for treatment of
palmar hyperhidrosis.
Phase:
Phase 1
Details
Lead Sponsor:
University of California, Davis
Treatments:
abobotulinumtoxinA Botulinum Toxins Botulinum Toxins, Type A incobotulinumtoxinA onabotulinumtoxinA