Overview

The Use of Metformin in Early Breast Cancer Patients Pre-Surgery

Status:
Withdrawn
Trial end date:
2016-02-01
Target enrollment:
0
Participant gender:
Female
Summary
The study will test metformin in patients with early breast cancer. Blood and tissue will be collected before and after the use of metformin.
Phase:
Early Phase 1
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Instituto Nacional de Cancer, Brazil
Treatments:
Metformin
Criteria
Inclusion Criteria:

- Invasive breast cancer T1 or T2, Nx

- Knowledge of the investigational nature of the study and ability to provide consent
for study participation

Exclusion Criteria:

- Diabetes or baseline glucose or Glycosylated haemoglobin upper limit of normal for the
institution

- Recent use of corticosteroids

- AST > 1.5 times upper limit of normal for the institution

- Pregnancy

- Serious clinical illness

- Prior or concurrent systemic neoadjuvant Breast Cancer therapy.