The Use of Inorganic Nitrate for the Prevention of Contrast-induced Nephropathy
Status:
Recruiting
Trial end date:
2021-10-01
Target enrollment:
Participant gender:
Summary
Contrast-induced nephropathy (CIN), an acute kidney injury resulting from the administration
of intravascular iodinated contrast media, is an important cause of morbidity/mortality
following coronary angiographic procedures in high-risk patients. Despite preventative
measures intended to mitigate the risk of CIN, there remains a need for an effective
intervention. Dietary inorganic nitrate therapy, which through its chemical reduction in the
body delivers nitric oxide has shown promise in attenuating CIN, but its effectiveness in
preserving long-term renal function is unknown.