The Use of Gastrografin to Help Alleviate Bowel Obstruction in Gastroschisis Patients.
Status:
Withdrawn
Trial end date:
2020-12-17
Target enrollment:
Participant gender:
Summary
This study will investigate the use of a drug called Gastrografin to aid in bowel mobility
for paediatric patients who have undergone gastroschisis surgery. Gastroschisis is an
abdominal wall birth defect where the bowel protrudes through a small opening beside the
umbilicus. In these patients, the bowel is often less mobile due to its exposure outside of
the body during fetal development. It is common for the bowel to be swollen and matted, which
decreases motility and makes it increasingly difficult for the baby to have normal bowel
function. Administering Gastrografin facilitates the entry of water into the intestines and
bowel, which is thought to aid in bowel function and motility. This study will compare
gastroschisis patients who received Gastrografin to gastroschisis patients collected as part
of an ongoing observational study at our centre who did not receive Gastrografin.