Overview

The Use of Eculizumab in HELLP Syndrome

Status:
Recruiting
Trial end date:
2023-01-04
Target enrollment:
Participant gender:
Summary
This research study is being performed to see if women diagnosed with early preterm Hemolysis, Elevated Liver Enzymes, Low Platelets (HELLP) syndrome (estimated gestational ages of 23-30 weeks) benefit from a medication called eculizumab (ECU). This drug blocks a part of the immune system called complement. By blocking this part of the immune system, eculizumab may stop or reverse the progression of the HELLP syndrome disease. The investigators will also look to see if this drug is effective and benefits both the mother and fetus.
Phase:
Phase 1
Details
Lead Sponsor:
Johns Hopkins University
Collaborator:
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Treatments:
Eculizumab