The Use of 5mg Finasteride Versus 200mg Spironolactone and Topical 5% Minoxidil in Treating Postmenopausal Female Androgenetic Alopecia

• Status: Withdrawn
• Trial end date: 2018-08-01
• Target enrollment: 0
• Participant gender: Female

Summary

The investigators propose to conduct a head-to-head, randomized clinical trial to compare the effectiveness of Minoxidil with Spironolactone and Finasteride in treating postmenopausal females with Androgenetic Alopecia (AGA).

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Florida
• Treatments: Finasteride; Minoxidil; Spironolactone

Criteria

Inclusion Criteria:

• female

• postmenopausal (>60 years old or with total hysterectomy)

• diagnosed with androgenetic alopecia

• no chemical processing or changes in hair products throughout the study

Exclusion Criteria:

• men

• premenopausal women (<60 or without hysterectomy)

• participants allergic to any of the study medications (minoxidil, finasteride, spironolactone)

• participants with other co-existing forms of alopecia (traction, alopecia areata, or scarring alopecias)

• participants with obstructive uropathy or advanced liver disease

• prior hair loss treatment within the last 6 months

• hair loss from the chemotherapy or other medication-induced alopecia

• Hair loss for greater than 5 years, as medical therapy is unlikely to have much effect at restoring hair follicles inactive for that long of a period.