Overview

The Trauma INtramuscular Tranexamic Acid Clinical Trial

Status:
Completed
Trial end date:
2020-02-12
Target enrollment:
Participant gender:
Summary
Intramuscular injection of tranexamic acid (TXA) would increase its use in situations where administration of intravenous drugs is difficult. The investigators aim to assess the population pharmacokinetics of intramuscular TXA in trauma patients. Primary endpoint: Serum TXA concentrations over time. Secondary endpoints: Local reactions at injection sites and adverse events
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
London School of Hygiene and Tropical Medicine
Collaborators:
Barts & The London NHS Trust
JP Moulton Charitable Foundation
St George's University Hospitals NHS Foundation Trust
University of Versailles
Treatments:
Tranexamic Acid