The Therapeutic Role of Intravenous Albumin Administration for Peptic Ulcer Bleeding Patients With Hypoalbuminemia

• Status: Completed
• Trial end date: 2011-08-01
• Target enrollment: 0
• Participant gender: All

Summary

To test whether intravenous albumin can decrease the rebleeding rate or shorten the duration of hospitalization in patients with peptic ulcer bleeding and hypoalbuminemia.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: National Cheng-Kung University Hospital
• Collaborator: National Science Council, Taiwan
• Treatments: Omeprazole

Criteria

Inclusion Criteria:

• Clinical presentations of melena, hematochezia, or hematemesis

• Gastroscopy confirmed peptic ulcers and major stigmata of recent hemorrhage

• A Rockal score ≥ 6

Exclusion Criteria:

• Gastric or esophageal, or duodenal tumor bleeding

• Ulcer due to mechanical factors

• Warfarin use

• Failure to establish hemostasis under gastroscopy

• Hypersensitivity to omeprazole, esomeprazole, albumin or any component of the formulation.