The Study of Regional Hemodynamic Changes After Specific Brachial Plexus Block by Ultrasound Guidance
Status:
Completed
Trial end date:
2012-12-01
Target enrollment:
Participant gender:
Summary
Phase 1 Sympathetic block leads to vasodilatation and increases in blood flow. However,
regional hemodynamic changes of radial and ulnar artery after specific nerve block of
brachial plexus remains unclear. The aim of the study is to assess the effect of specific
nerve block of brachial plexus on hemodynamics of upper extremity, and provides evidence for
further research in patient undergoing microvascular surgery.
Phase 2 There is no literature about dose-finding studies of sympathetic block after brachial
plexus block. Little is known regarding the relationship between concentration of local
anaesthetic and vasodilation of upper extremity. The aim of this randomized, double-blind,
prospective dose-response study is to determine the ED50 and ED95 of ropivacaine in
sympathetic block of upper extremity after supraclavicular block
Phase:
Phase 1
Details
Lead Sponsor:
Wenzhou Medical University
Collaborator:
Health and Family Planning Commission of Zhejiang Province, China