Overview

The Study of Inflammation on Blood Glucose Levels in Obese People

Status:
Completed
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
Chronic subaccute inflammation may underlie the development of diabetes cardiovascular disease and other components of the metabolic syndrome. Rodent studies suggest diet induced obesity is associated with activation of the IKK/NF-kB pathway and this pathway can be inhibited by salicylates. This study seeks to determine the effect of salicylates in overweight persons.
Phase:
Phase 2
Details
Lead Sponsor:
Joslin Diabetes Center
Collaborator:
National Institutes of Health (NIH)
Treatments:
Salicylsalicylic acid
Sodium Salicylate