The Study of Different Sedative Medications in Monitored Anesthesia Care During Eye Surgery With Local Anesthesia
Status:
Recruiting
Trial end date:
2021-12-31
Target enrollment:
Participant gender:
Summary
Due to the delicacy and long duration of the procedure, ophthalmic surgery put forward higher
requirements to anesthesia management:
1. The patient with local anesthesia without sedation is in a state of awareness, which
will cause intense stress resulting in increased blood pressure, heart rate, muscle
tension and even sense of pain;
2. Traction of extraocular muscles and eyeballs can induce oculocardiac reflex, followed by
bradycardia, atrial or ventricular arrhythmia, conduction block, and even more worsen,
life-threatening cardiac arrest may occur;
3. With the increase in average life expectancy and the improvement of quality of life
requirements, the number of elderly patients in ophthalmic surgery is also increasing.
These elderly patients are often combined with hypertension, diabetes, etc. and
decreased tolerance of with general anesthesia;
4. For some retinal detachment surgery with difficulty in resetting, the patients will be
required to change to the prone position immediately after surgery to improve the
success rate of resetting. Conventional general anesthesia management are cumbersome and
costly, which may not be likely to achieve the swift emergence.
Nowadays, monitoring Anesthesia Care (MAC) has developed into a flexible and unique
anesthesia technology combining intravenous anesthesia with regional block anesthesia. MAC
provides reasonable balance between economy, comfort and safety, efficiency by continuous
monitoring of changes in respiratory and circulatory system, during process of sedation and
analgesia. Airway management will be another issue as surgeons operate on the side of head
and face. Studies have shown that MAC can achieve adequate sedation and analgesia to decrease
blood pressure, provide acceptable surgical fields and reduce adverse reactions such as
perioperative stress, pain and anxiety. Meanwhile, MAC make patients comfortable enough to
cooperate with the surgeons, easy to be awakened with relatively short operation duration and
improvement of perioperative safety.