The Significance of Deviation in Time From the 12-hour Standard Serum-clozapine Monitoring.
Status:
Completed
Trial end date:
2016-02-01
Target enrollment:
Participant gender:
Summary
The role of Therapeutic Drug Monitoring (TDM) in clozapine dose adjustment have been debated.
Blood samples for s-clozapine monitoring should be drawn 12 hours post dose.
The scope of this trial is to describe changes of s-clozapine and s-N-desmethyl-clozapine
within the range of 10-14 hours after the last administration of clozapine .