The Serotonin Transporter Availability for Prognosing Major Depressive Disorder (MDD) Treatment and Detecting MDD
Status:
Completed
Trial end date:
2012-11-01
Target enrollment:
Participant gender:
Summary
Objectives:
1. To evaluate the relationship between improvement of Hamilton Depression Rating Scale
(HAMD) score and basal SERT availability (binding potential) for the prognosis of MDD
subjects being treated with Sertraline HCl
2. To evaluate the SERT availability by means of I-123-ADAM SPECT imaging study for
assisting in detecting MDD
3. To evaluate the relationship between basal HAMD score and basal SERT availability for
MDD subjects
4. To evaluate the relationship between basal HAMD somatic subscale score and basal SERT
availability for MDD subjects
5. To evaluate the relationship between change of SERT availability and change of HAMD
score for MDD patients being treated with Sertraline HCl