Overview The SPECTRA Study Status: Terminated Trial end date: 2003-06-01 Target enrollment: Participant gender: Summary The purpose of this study is to compare IL-1ra and the combination of IL-1ra and PEGsTNF-RI with respect to their ability to reduce inflammation and bone and cartilage destruction in the synovium of subjects with rheumatoid arthritis. Phase: Phase 2 Details Lead Sponsor: AmgenTreatments: Interleukin 1 Receptor Antagonist Protein